Presentationfontcache.exe is a is a Windows Presentation Foundation Service from Microsoft Corporation belonging to .NET Framework 3. Many windows users complained about presentationfontcache.exe consuming high CPU usage.
As you know now that presentationfontcache.exe is a part of .net framework 3 and it is very much required for some applications to work properly. You should not disable it as it is highly recommended to run it.
If presentationfontcache.exe is a using very high CPU then you can try killing the process temporarily, but please note that it will start automatically after some time, you can refer our guide to block an executable to run here. Still if you want to stop presentationfontcache.exe, then you can refer some discussion here and here