By default Skype Windows or MAC OSX user interface programs shows the notifications of your Skype friends whenever they come online. You may feel disturbed by these notifications when they appear while were working on some thing very important.
In such a case you can simply disable these notifications, or customize them as per your preference under Skype options. Follow the steps given below to disable off Skype notifications
1. Open Skype interface, and login to your Skype account
2. Now go to Skype >> Tools >> Options
3. Under Skype options click the Notifications settings on the left pane, un-check the Skype notifications which you want to turn off so that there is no distraction while you are working.
4. Click Save button to close the window and save your preferences for future.